Male Birth Control Pill Shown to Be Safe in Early Trials

Contraceptive Pills For Men Will Become A Reality As The Trials Revealed Positive Results

Contraceptive Pills For Men Will Become A Reality As The Trials Revealed Positive Results

The technical term for the oral contraceptive for men is dimethandrolone undecanoate, or DMAU, for short.

Prototype tablets are more attractive to many men than long-acting injections or topical gels, prototype pills are a male contraceptive "Stephanie Page", a professor survey at the University of Washington in Seattle The investigator said in a statement.

The tests revealed that the pill does not result in significantly negative side effects, but more research may be needed to further establish it as safe and effective. The levels of these hormones matched long-term studies on male birth control that was found to be effective in the past, and researchers found "very few subjects reported symptoms consistent with testosterone deficiency or excess".

The study found that men who took the highest dose of DMAU, 400 mg, showed "marked suppression" of levels of testosterone and two hormones required for sperm production: luteinizing hormone and follicle-stimulating hormone.

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Page says a second study of DMAU will involve 100 men, 50 in Washington and 50 in California. DMAU is being developed by the National Institutes of Health, Eunice Kennedy Shriver National Institute of Child Health and Human Development, which funded this study. This is why another male contraceptive just straight up blocks sperm; it only takes one to cause pregnancy, after all.

The pill was also well tolerated, with groups taking DMAU experiencing slight weight gain and decreases in "good" cholesterol levels, but these effects were mild, Dr. Page said.

Different doses of the pill were given to 83 men over the course of 28 days.

The findings of the research were presented at the Endocrine Society's annual meeting in Chicago. Unlike other forms of oral testosterone, which classically are cleared from the body quickly, this compound contains a specific long-chain fatty acid that slows this clearance making it a flawless "once-a-day" pill.

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The journey of creating such a pill has not been free of challenges that puzzled the scientists but they have managed to pass over them and to reach the point at which they were able to produce 100% working and safe contraceptive pills for men.

The race is on to develop a male contraceptive drug similar to that of the female birth control pill. DMAU must be taken with food to be effective, Page noted.

The researchers are now conducting longer-term studies on the efficacy and safety of DMAU. She added the current trial was to determine if the pill could be taken safely for more than one dose, but did not test its effectiveness as a contraceptive.

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